The former vice president was declared the winner of the election in November, after days of vote counting and uncertainty.
As Biden prepares to relieve President Donald Trump of his role after just one term, the 78-year-old has stated his intention to overturn a number of Trump laws (the 'Muslim ban', the transgender military ban and rejoining the Paris Climate Accord, to name a few) and will implement a number of swift responses to the COVID-19 pandemic.
The promised policy changes have been a consistent line throughout Biden's campaign. And so has his experience with grief and hardship.
Before his campaign for the presidency, many of us knew the 78-year-old as Barack Obama's friendly sidekick. But in private, Biden's life has been full of tragedy.
The loss of Joe Biden's first wife and their daughter.
Joe Biden was still a law student when he married Neilia Hunter in 1966. Together they had three children: Beau, Robert (Hunter) and Naomi.
In 1972, he won the US Senate election in Delaware, despite seemingly having no chance of winning. It was his biggest professional success so far, and his beautiful young family were thought to have attracted voters.
But just weeks later, while his wife was purchasing a Christmas tree with their children, she was killed in a car accident, along with their youngest child, one-year-old Naomi.